Does the Route of Feeding Modify Gastric Emptying in Rats?
Guoxiang Shi, MD, PhD Centre de Recherche en Nutrition Humaine, CRI-INSERM 95/08 CHU Hôtel-Dieu, Nantes Christine Cherbut, PhD Centre de Recherche en Nutrition Humaine, CRI-INSERM 95/08 CHU Hôtel-Dieu, Nantes Stanislas Bruley des Varannes, MD, PhD Centre de Recherche en Nutrition Humaine, CRI-INSERM 95/08 CHU Hôtel-Dieu, Nantes Claude Rozé, PhD INSERM U 410, Faculté X Bichat, Paris, France Jean Paul Galmiche, MD, FRCP Centre de Recherche en Nutrition Humaine, CRI-INSERM 95/08 CHU Hôtel-Dieu, Nantes Background: It has been shown that the pattern of previous nutrient intake can influence gastric emptying. However, the effect of the absence of enteral stimulation in the setting of a normal energy supply on gastric emptying has not been examined. The aim of this study was to determine whether the absence of enteral stimulation during total parenteral nutrition (TPN) could modify gastric emptying in rats. Methods: Two experiments were performed. First, gastric emptying of a peptone meal was
