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Does the exhaust from the room air returns as well as the exhaust from the hood need to be HEPA filtered and exhausted 100% outside in negative pressure hazardous drug buffer rooms?

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Does the exhaust from the room air returns as well as the exhaust from the hood need to be HEPA filtered and exhausted 100% outside in negative pressure hazardous drug buffer rooms?

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No. The exhaust from the BSC must be HEPA filtered. Class II BSCs and CACI’s are equipped with HEPA filters in the exhaust. Additional HEPA filtration typically is not required.

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