Does sucralose cause headaches/migraines?
No. Research does not support that sucralose causes migraines or headaches. There are no adverse effects expected with sucralose use. Headaches and migraines are very common events in people and can be caused by many things. Sucralose is not known to produce changes in the body that are associated with headaches or migraines. For example, sucralose has no known effects on vasodilation (opening of blood vessels) or blood pressure. Studies show no effect on blood glucose or insulin levels and there are no known effects on the nervous system.