Does severe teratozoospermia affect blastocyst formation, live birth rate, and other clinical outcome parameters in ICSI cycles?
OBJECTIVE: To determine if strict morphology correlates with outcome parameters in couples undergoing intracytoplasmic sperm injection (ICSI). DESIGN: Retrospective review. SETTING: Academic nonprofit IVF center. PATIENT(S): Couples undergoing IVF/ICSI. INTERVENTION(S): In vitro fertilization and ICSI. MAIN OUTCOME MEASURE(S): Samples were evaluated for total sperm count, motlity, progression, and morphology using Kruger’s strict criteria. The ICSI cycle outcome parameters included fertilization, clinical pregnancy, implantation, live birth, and blastulation rates and blastocyst quality. RESULT(S): Fertilization rates were high (74%-77%), and clinical pregnancy rates ranged from 60% (subgroup with 0% normal sperm) to 56% (subgroup with >/=7% normal forms). The highest pregnancy and live birth rates were observed in eggs fertilized with sperm from specimens with the most severe teratozoospermia. The blastulation rate was similar among subgroups. The percentage of high-quality blastocyst
Related Questions
- For couples with severe male factor infertility, does the diagnosis of the severe male factor problem affect the live birth rate for these couples using IVF and ICSI?
- Does severe teratozoospermia affect blastocyst formation, live birth rate, and other clinical outcome parameters in ICSI cycles?
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