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Does severe pancreatitis cause the pancreas to stop producing insulin? Does it weaken the pancreas enough?

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Does severe pancreatitis cause the pancreas to stop producing insulin? Does it weaken the pancreas enough?

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Yes. Severe pancreatitis with necrosis (death of parts of the pancreas) can cause endocrine and exocrine dysfunction meaning that insulin and other pancreatic enzymes may no longer be produced due to the severe damage to the pancreatic tissue. A complication of pancreatitis is the development of diabetes which may require insulin and also pancreatic insufficiency which may require replacement of the pancreatic enzymes which help with digestion.

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