Does routine PSA testing decrease prostate cancer mortality?
Collin SM et al. (2008) Prostate-cancer mortality in the USA and UK in 1975–2004: an ecological study. Lancet Oncol 9: 445–452 The uptake of PSA screening since its introduction around 1990 has been markedly different in the USA and UK (57% vs 6%, respectively, by 2001); therefore, an effect of screening on prostate cancer mortality might be revealed by a comparison of these countries’ prostate cancer mortality rates.