Does PubGene also deal with DNA- and protein sequences?
Many genes identified by sequencing efforts remain to be described in terms of the function of their products. In such cases you may be able to guess the function of the gene of interest by looking at similar genes. DNA- and protein sequences are also useful for experiments aimed at validating your results, e.g. as primer sequences for RT-PCR. Generally, to find similar genes you look for genes with similar structure (that is, similar nucleotide or amino acid sequence). PubGene can draw networks based on sequence similarity. This function is available under Advanced Options in Bio Networks. PubGene sequence networks are based on pair-wise alignment of reference sequences in a pre-compiled database. By viewing a sequence network you can quickly see if other genes with similar sequence have been described in terms of their biological or medical importance. You can also perform searches of sequence databases with the PubGene Sequence Homology tool. This tool aligns a DNA or protein sequen
Many genes identified by sequencing efforts remain to be described in terms of the function of their products. In such cases you may be able to guess the function of the gene of interest by looking at similar genes. DNA- and protein sequences are also useful for experiments aimed at validating your results, e.g. as primer sequences for RT-PCR. Generally, to find similar genes you look for genes with similar structure (that is, similar nucleotide or amino acid sequence). PubGene can draw networks based on sequence similarity. This function is available under Advanced Options in the Network Browser. PubGene sequence networks are based on pair-wise alignment of reference sequences in a pre-compiled database. By viewing a sequence network you can quickly see if other genes with similar sequence have been described in terms of their biological or medical importance. You can also perform searches of sequence databases with the PubGene Sequence Homology tool. This tool aligns a DNA or protein
