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Does PSA Velocity Affect Prostate Cancer Risk?

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Does PSA Velocity Affect Prostate Cancer Risk?

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There are two very different theories about this. One group, represented by Dr. William Catalona and colleagues, believes that PSA velocity is a strong indicator of risk for aggressive prostate cancer, and that men with a rapidly rising PSA are at greater risk for aggressive disease that needs treatment than men with a slowly rising PSA. Another group, represented by Michael Vickers and colleagues, believes that PSA velocity is irrelevant to prostate cancer risk by comparison with other available data, and that we don’t need the PSA velocity to tell us who is at risk because we already know. The “New” Prostate Cancer InfoLink is neutral. We believe that it should be possible to resolve this issue fairly easily with the right data analysis (see discussion on blog entry from June 2008).

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