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Does prophylactic pancreatic stent placement reduce the risk of post-ERCP acute pancreatitis?

April 26, 2017acute pancreatic pancreatitis placement post-ercp prophylactic reduce risk stent

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Does prophylactic pancreatic stent placement reduce the risk of post-ERCP acute pancreatitis?

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Singh P, Das A, Isenberg G, Wong RC, Sivak MV, Agrawal D, Chak A. Division of Gastroenterology, University Hospitals of Cleveland. Cleveland, Ohio, USA. Impaired drainage of the pancreatic duct is one of the possible triggers for post-ERCP acute pancreatitis. The aim of this meta-analysis was to determine whether temporary stent placement across the main pancreatic-duct orifice lowers the frequency of post-ERCP acute pancreatitis in patients at high risk for this complication. Two reviewers systematically identified prospective studies that (1) compared the risk of post-ERCP acute pancreatitis in patients with pancreatic stent placement vs. no stent placement and (2) included patients at high risk of developing this complication. Studies were assessed for methodologic quality and variations in execution and design. Frequency and severity of post-ERCP acute pancreatitis were the primary outcomes evaluated. Results Five trials involving 481 patients were selected. Of the 481, 55 (11.4%)