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Does prophylactic cranial irradiation reduce the incidence of brain metastases in extensive small-cell lung cancer?

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Does prophylactic cranial irradiation reduce the incidence of brain metastases in extensive small-cell lung cancer?

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Original article Slotman B et al. (2007) Prophylactic cranial irradiation in extensive small-cell lung cancer. N Engl J Med 357: 664–672 PubMedBrain metastases are common in patients with small-cell lung cancer and indicate a poor prognosis.

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