Does PLoS Genetics consider studies utilizing computational genetics or bioinformatics approaches?
We certainly recognize the increasing reliance upon computational work in genetics and genomics investigations, ranging from methods (simulations), to database mining, to comparative sequence analysis. However, the journal encourages “hybrid” studies that also have a strong experimental (that is, “wet bench”) component as well, for example, to validate or further support the conclusions. Purely computational studies, and even some hybrids, might be equally or better suited to PLoS Computational Biology or PLoS ONE.