Does Photosensitivity Predict Photococarcinogenicity?
Abigail Jacobs Division of Dermatologic and Dental Drug Products, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Rockville, MD, USA Javier Avalos Division of Dermatologic and Dental Drug Products, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Rockville, MD, USA Paul Brown Division of Dermatologic and Dental Drug Products, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Rockville, MD, USA Jonathan Wilkin Division of Dermatologic and Dental Drug Products, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Rockville, MD, USA Assessment of short-term and long-term effects of light (pho—totesting) is part of the safety evaluation of drugs. Results are incorporated into drug package inserts to advise patients and health care providers about the use of drug products on sun—exposed skin. We undertook an exhaustive literature search and a search of archived studies at the Center for D
