Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

Does PB Cross the Blood-Brain Barrier During Conditions of Stress?

April 26, 2017barrier blood-brain Conditions cross Pb stress

0

Posted

Does PB Cross the Blood-Brain Barrier During Conditions of Stress?

1 Answer

0

Posted

PB is normally viewed as having minimum potential for CNS toxicity, due to its failure to cross the blood-brain barrier. However, recent evidence suggests this failure to cross the blood-brain barrier is vitiated under conditions of stress (Friedman, Kaufer, et al., 1996; Hanin, 1996) and possibly with administration of multiple chemicals. Therefore, central effects of PB may contribute to symptoms.