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Does osmolarity correlate to symptoms of Dry Eye Disease?

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Does osmolarity correlate to symptoms of Dry Eye Disease?

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In DED, it is known that symptoms correlate poorly with objective signs. It is important to note that in the absence of symptoms the presence of hyperosmolarity is still evidence of DED. Hyperosmolarity in the absence of symptoms should be considered an abnormality in the body’s homeostatic osmoregulation and a sign of DED.

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