Does OMIM contain information on chromosomal aberrations?
No, although there are a few exceptions. OMIM contains records about human genes and genetic disorders that are inherited in a Mendelian manner. Genetic conditions that are due to a chromosomal aberration, such as monosomy or trisomy, generally do not have entries in OMIM. There are a couple of chromosome aberrations (Trisomy 21 and cri-du-chat) which have been given an entry in OMIM for historic or other reasons; however, monosomy or trisomy of any chromosome would not normally be included in the database. For information on chromosomal aberrations, see Schinzel, Albert: Catalog of Unbalanced Chromosomal Aberrations in Man. de Gruyter, 1984. In addition, a genome-wide map of chromosomal breakpoints in human cancer, by Drs. Mitelman, Mertens, and Johansson is available on the NCBI web site. It is a hypertext version of a recent special issue of Nature Genetics, Vol. 15(Spec. No.):417-74 (April 1997). The Mitelman Breakpoint Map is also displayed graphically in the Entrez Map Viewer. Wh
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