Does N-acetylcysteine have any toxicity?
A. As far as I know, no significant side effects or toxicity have been reported. Q. How does glutathione affect inflammation? A. NF-κB is a transcription factor that turns on a lot of genes involved in the immune response, acting as a master regulator of immune response. NF-κB is redox sensitive oxidative stress can activate it, which causes the expression of genes that cause inflammation. That, in turn, produces more oxidative stress that further amplifies the process. Glutathione or other antioxidants may help break that cycle by stopping the oxidative stress, attenuating NF-κB activation, and breaking the endless cycle of self-propagating chronic inflammation. We think that zinc also inhibits NF-κB activation. Q. How might zinc protect against diabetes? A. Zinc plays a big role in helping to maintain a healthy immune system. It also acts as an antioxidant and stops some of the proinflammatory effect of NF-κB. Q. Are diabetics zinc deficient? A. Not many studies have examined zinc st
