Does monitoring bispectral index or spectral entropy reduce sevoflurane use?
Author(s): Aime I, Verroust N, Masson-Lefoll C, Taylor G, Laloe PA, Liu N, Fischler M Affiliation(s): Department of Anesthesiology, Hopital Foch, 40 rue Worth, 92151 Suresnes, France. Publication date & source: 2006-12, Anesth Analg., 103(6):1469-77. Publication type: Randomized Controlled Trial A decrease in volatile anesthetic consumption has been demonstrated using bispectral index (BIS), whereas data concerning spectral entropy are lacking. One hundred and forty adult patients scheduled for surgical procedures lasting more than 1 h were prospectively randomized to receive an anesthetic controlled either by BIS or by spectral entropy or solely by clinical variables. Anesthesia was induced with propofol and sufentanil. Sufentanil was infused continuously thereafter. Sevoflurane was administered in 1 L/min O2/N2O. The sevoflurane concentration was adjusted according to conventional clinical variables in the standard practice group, whereas the 40-60 interval was applied for the BIS an
