Does methadone/Suboxone interact with other medications?
Pharmacotherapy is increasingly complicated by the introduction of new drugs and the use of multi drug regimes for acute chronic diseases. During clinical use spanning over 35 years, oral methadone has proven to be a well tolerated medication with minimal reactions when prescribed in appropriate doses and in combination with other drugs, however there are certain drugs that produce adverse affects when used with methadone either by increasing or decreasing its affect. It is imperative that you inform CDHS staff and your primary care physician (PCP) of all medications. Methadone drug interactions may occur when taking prescribed medications, illicit drugs, OTC products, and other substances that can be difficult to predict and may be potentially harmful. A list of drugs that interact with methadone can be obtained at any methadone clinic and possible at your doctors office. A list will be provided to you upon request.