Does methadone make a person irritable, angry, confused, etc.?
No, it will seldom make a patient irritable, angry or confused. On the contrary, it is great as an anti-depressant. And, unlike short-acting opiates, it boosts the immune system. Often doctors will refuse to treat an AIDS patient if s/he is on methadone. Many doctors are unfortunately ignorant of the fact that methadone, a long-acting opiate, is unlike short-acting opiates in that area (short-acting opiates depress the immune system). AIDS patients in particular should remain on methadone.