Does long term intravesical oxybutynin treatment of hyperreflexic neurogenic bladder result in bladder auto-augmentation?
The main goal of the treatment of neurogenic bladder is to promote continence and protect the upper urinary tract from deterioration. Conversion of a hyperreflexic detrusor to a lower pressure detrusor could be reached by the use of anticholinergic medication and clean intermittent catheterization (CIC). Important alternative to reduce side effects and lower the detrusor pressure is the intravesical administration of oxybutynin. The presented study investigated the urodynamic effects of the long-term administration of intravesical oxybutynin in hyperreflexic neurogenic bladder to evaluate the property of bladder auto-augmentation.
