Does Jadelle use increase the risk of gallbladder disease?
Some studies have reported an increased lifetime relative risk of gallbladder disease in users of oral contraceptives and estrogens. More recent studies, however, have shown that the relative increased risk of developing gallbladder disease among oral contraceptive users is minimal. These recent findings may be related to the lower doses of estrogens and progestins in current pill formulations. In the Norplant postmarketing surveillance study, the relative risk of gallbladder disease was moderately higher in Norplant users in Chile and China compared with women in the control groups.
