Does it make a difference whether to apply the image optimization directly in SilverFast or later in Photoshop?
Yes, it does. It is better to apply all the image corrections as early as in the SilverFast interface, because SilverFast is using the entire dynamic range of the hardware (scanner) thus applying all corrections on the true data BEFORE this data is “compressed” into 8bit data and transfered to the computer’s harddrive or into the host application. SilverFast optimizations will NOT effect the data dynamic and no losses in tonal values occur, as would be the case when optimizing a ready-scanned 8bit file.