Does irradiation affect the clinical outcome of patellar tendon allograft ACL reconstruction?
The clinical implications of using irradiation to sterilize allograft bone-patellar tendon-bone (BPTB) remains unknown. The purpose of this study was to compare the clinical outcome of anterior cruciate ligament (ACL) reconstruction with irradiated allograft versus autograft BPTB. We hypothesized that patients undergoing ACL reconstruction with irradiated BPTB allograft would have no significant differences in patient-reported and objective parameters compared to those undergoing autograft BPTB reconstruction. Patients who underwent ACL reconstruction with either irradiated allograft or autograft BPTB from 1996 to 2002 were eligible for this study. One hundred and two patients (39 allograft, 63 autograft) met the study criteria and were available for follow-up. The BPTB allografts were obtained from a single tissue bank and were sterilized with 2.5 Mrad of irradiation prior to distribution. Participants completed the International Knee Documentation Committee (IKDC) subjective knee for
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