Does INTREPID use any information from experimental studies or 3D structure?
At this point, the INTREPID algorithm does not use experimental evidence or 3D structure to infer functional sites; INTREPID relies only on patterns of evolutionary conservation across the protein family phylogeny. For this reason, INTREPID can be used in cases that lack experimental evidence or solved 3D structures. INTREPID does make use of homologous 3D structures to display functional residue prediction, but this information is not used to make the predictions.
Related Questions
- Is there experimental evidence that the potency of siRNAs is influenced by target accessibility and secondary structure?
- Is there experimental evidence that the potency of siRNAs is influenced by target accessibility and secondary structure?
- Are the results given by online bending moment calculator http://civilengineer.webinfolist.com/mech/bmcalc.htm acceptable
- Why does the structure page linked from the phylogenomic analysis not have the INTREPID results?
- Why does the structure page linked from the phylogenomic analysis not have the INTREPID results?
- Does INTREPID use any information from experimental studies or 3D structure?
