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Does Institutional Review Board (IRB) approval need to be approved at the time of proposal submission or can it just be submitted?

Approval Approved institutional IRB proposal review submission submitted time
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Does Institutional Review Board (IRB) approval need to be approved at the time of proposal submission or can it just be submitted?

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Applicants must follow their own institution’s IRB rules and must get IRB review and approval when appropriate for their project.

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