DOES INFLUENCE ERYTHROCYTE FUNCTION AND MORPHOLOGY THE USE OF HYPERTONIC SALINE SOLUTION IN POST HEMORRHAGIC SHOCK TREATMENT?
The purpose of this study was to establish the influence of hypertonic saline solution 7,5% perfusion on erythrocyte function and morphology in condition of post hemorrhagic hypovolemic shock state on dogs. The research was carried out on 22 indefinite half-breed dogs on which under anesthesia, were induced the hemorrhagic shock, and the reequilibration therapy with hypertonic saline solution administrated by intravenous or intra-arterial route was applied. In order to highlight the changes of the erythrocyte diameter were prepared some blood smears, colored May-Grünwald-Giemsa, that were examined with a 90 object lens. The pulse oximetry assessing brings us information about the gas exchange at pulmonary level and indirectly about erythrocyte capacity to binding and carrying oxygen. The obtained results demonstrates the fact that the use of hypertonic saline solution does not compromise the erythrocyte function and in context of microcirculatory changes associated with shock state the
