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Does hyperthyroidism predispose to thioridazine-induced hyperpyrexia and cardiac arrhythmias?

April 26, 2017arrhythmias cardiac Hyperthyroidism predispose thioridazine-induced

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Does hyperthyroidism predispose to thioridazine-induced hyperpyrexia and cardiac arrhythmias?

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Treatment with thioridazine resulted in hyperpyrexia and ventricular tachycardia in a young woman who was later shown to have thyrotoxicosis. The reasons why hyperthyroidism may enhance thioridazine toxicity are reviewed.