Does GenScript guarantee that the recommended siRNA constructs will work?
About 95% of the custom siRNA constructs made by GenScript and designed at the GenScript siRNA Design Center show potent target inhibition, 70% or better, when tested in groups of three. The most common cause of siRNA failure is low transfection efficiency. To deal with this problem, GenScript has developed GFP-marked vectors to track and confirm transfection efficiency. However, because of the uncertainly involved in transfection experiments, GenScript does not guarantee that all its siRNA constructs will work.
