Does female gender increase the sensitivity to QT-prolonging drugs and raise the risk of torsades de pointes with some drugs?
Yes it does. Even at equivalent blood levels of the drugs, females have an increased sensitivity to drugs that prolong the QT interval and have a higher incidence of torsades de pointes. Look for comments regarding gender for specific drugs on our lists: Please click here to view the lists. PubMed searches on this topic area are available on our site.
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