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Does epileptiform activity contribute to cognitive impairment in Alzheimers disease?

April 26, 2017activity Alzheimer's disease cognitive contribute epileptiform impairment

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Does epileptiform activity contribute to cognitive impairment in Alzheimers disease?

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Alzheimer’s disease is a devastating neurological disorder. The role of hyperexcitability in the disease’s cognitive decline is not completely understood. In this issue of Neuron, Palop et al. report both limbic seizures and presumed homeostatic responses to seizures in an animal model of Alzheimer’s.