Does early treatment with antihypertensive drugs improve outcome post-ischemic stroke?
• Should we lower blood pressure more aggressively in hemorrhagic stroke? Background Blood pressure management in the early phase of stroke (within 7 days) is still a debated issue. Both high blood pressure and low blood pressure in acute ischemic stroke are independent prognostic factors for poor outcome [1]. It remains unclear whether blood pressure in acute ischemic stroke should be modified, and if so, what would be the optimal range. Discussion In acute ischemic stroke: should previous antihypertensive drugs be continued or stopped temporarily? High blood pressure in acute ischemic stroke may improve cerebral blood flow and outcome, as suggested by animal experiments and small proof-of-concept studies in patients [2]. In many centers it is common practice either to continue or to stop antihypertensive drugs temporarily. Many questions are still unanswered about the safety and potential benefits of this method. Two RCTs investigate the effects on outcome of stopping versus continui
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- Does early treatment with antihypertensive drugs improve outcome post-ischemic stroke?
