Does drinking a lot of water really affect urine drug tests?
Drinking a lot of water can temporarily dilute urine for a short period of time. If a drug or metabolite is excreted in small concentrations, near the cutoff, it is possible to cause a negative screen. For instance, with a 50 ng/ml cutoff for carboxy-THC, a patient with a metabolite concentration of 52 ng/ml might be able to dilute their urine to 49.2, and have good fortune on that particular screen. However, a person with 5000 ng of oxycodone with a 100 ng/ml cutoff will not significantly change their screening outcome by excessive ingestion of water.