Does diphenhydramine show up in drugs test?
This is the common ingredient in Benedryl and sleep aids like Unisom. While it is available over the counter, it is also available in prescription strength. It will not show up on a drug test as diphenhydramine, but could possibly show up as some type of opiate. It is best to alert the person administering the test that you have been taking it and in what form it was taken. It is not illegal, and being honest will keep you out of possible scrutiny or trouble.