Does convective dialysis therapy applied daily approach renal blood purification?
Outcome studies in dialysis have generally failed to show an impact of changes in membrane flux or bio-compatibility, and only dose increases up to a certain level have been shown to improve survival significantly. However, to see an effect of a potentially improved dialysis treatment, all available factors that make dialysis more physiological may need to be combined. A membrane that mimics the glomerular basement membrane in being hemocompatible, having a high hydraulic permeability and a generous sieving, yet not leading to albumin loss could be used. The dialysis fluid composition could be individualized, and the quality and volume appropriate for the selected application. The new system of online-prepared ultrapure dialysis fluid and sterile infusion solutions, as integral parts of the treatment, are cost effective and labor saving as well as biocompatible. Ideally, we should select a blood purification method that covers the same range of solutes as the kidney. Convection is equa
