Does Combined Multichannel Intraluminal Esophageal Impedance and Manometry Predict Postoperative Dysphagia after Laparoscopic Nissen Fundoplication?
Purpose: The purpose of this study was to identify if the addition of multichannel intraluminal esophageal impedance (MII) to manometry may detect those patients most at risk of developing postoperative dysphagia.Methods: Between March 2003 and April 2006, 69 patients who agreed to participate in this study were prospectively enrolled. All patients completed a pre-operative symptom questionnaire, MII/manometry, and 24-hour pH monitoring. Symptom questionnaires were administered post-operatively at a median of 18 months (range: 6–46 months), and we defined dysphagia (both preoperative and postoperative) as occurring more often than once a month with a symptom severity score (SSI – scale = 0–10) 4. LNF was performed in all cases.Results: Thirty patients (43%) reported pre-operative dysphagia. There was no significant difference in pH monitoring, lower esophageal sphincter (LES) pressure/relaxation, peristalsis, liquid or viscous bolus transit, or bolus transit time between patients with
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