Does clomiphene have any negative effects on fertility?
It can. By blocking estrogen’s activity in the uterus, the lining may be inadequately prepared for implantation of the embryo. Many women also find that their cervical mucous suddenly becomes hostile to sperm penetration. How well does clomiphene work? In women who need clomiphene to ovulate, the pregnancy rates are very high, as much as 33% per cycle for the first three cycles. In women who normally ovulate the rates are lower, and depend on many other factors, chiefly age, condition of the female reproductive tract and the male factor.
