Does clomiphene cause any other problems?
Research studies years ago seemed to show a link between using clomiphene for long periods of time (1 year or more) and cancer of the ovary. More recent studies have not shown such a link. This is still being studied. Sometimes the drug may cause changes in the cervical mucus that make it hard for sperm to get into the uterus. In this case you may need to take low doses of the female hormone estrogen along with clomiphene. There have been no reports of more birth defects in babies whose mothers took clomiphene than in normal pregnancies. Fertility drugs are expensive and may not be covered by health insurance. It is important for you to decide what treatments you can afford, both emotionally and financially, as you think about treatment for infertility. Discuss your feelings and concerns with your provider before you begin treatment. For more information, check The National Infertility Association’s Web site at http://www.resolve.org.