Does Cleome droserifolia have anti-schistosomiasis mansoni activity?
El-Shenawy NS; Soliman MF; Abdel-Nabi IM Zoology Department, Faculty of Science, Suez Canal University, Ismailia, Egypt. elshenawy_nahla@hotmail.com The present study was undertaken to assess the effect of the crude extract of Cleome droserifolia (CD) leaves on experimentally infected mice with Schistosoma mansoni. Two groups of mice, showing a patent infection of S. mansoni, one of them was daily treated with an alcoholic extract of CD leaves (0.31 g kg-1 body weight, i.p.) for 21 days. The schistosomicidal activity of the CD extract was evaluated, three weeks post-treatment, on some parasitological and histopathological aspects including worm load, oogram pattern, faecal eggs releasing and granuloma formation. In addition, serum thyroid hormones levels (tri-iodothyronine; T3 and tetra-iodo-thyronine; T4), serum total protein contents and hepatic reduced glutathione (GSH) were evaluated. Treatment using CD extract resulted in a weak reduction in worm burden (32.46%) and affected the v
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- Does Cleome droserifolia have anti-schistosomiasis mansoni activity?
