Does capsaicin cause physical damage?
No. The burning sensation that comes from capsaicin is a result of neuropathic signals, not physical damage. When eating chili peppers or “hot” chicken wings, people will experience a burning sensation in their mouths. However, approximately thirty minutes after eating, the membranes in the mouth have returned to normal, experiencing no lasting discomfort. While its effects can be highly irritating, they are temporary. Capsaicin is non-toxic and has been used for many years in a wide variety of products to include arthritis medicines, as well as pepper sprays used by police. The number one use of oleoresin of capsicum is still as a flavor additive (spicy seasonings) in cooking.