Does caffeine negate the effects of creatine?
Many believe that caffeine will interfere with the effectiveness of creatine. There are a few reasons for this belief. The primary reason is that one study published in 1996 found that while muscle phosphocreatine concentrations were increased by both supplementation with creatine and supplementation with creatine and caffeine for six days, there was a significant improvement in dynamic torque production only in the group that consumed creatine but not caffeine. A second study found that caffeine, which increases muscle relaxation time, kept creatine from decreasing muscle relaxation time. and and The results of these studies should be treated with caution. In the study that indicated that caffeine may block the effects of creatine, there were only nine subjects, divided into three groups (placebo, creatine, creatinecaffeine). Another double-blind study (Gill et al.), although not appearing in the peer reviewed literature, compared the effect of creatinecreatine plus caffeine on maxima
