Does aspirin really improve breast cancer survival?
Only a clinical trial, in which randomly assigned treatment is tested against an inactive placebo, can prove that a treatment is truly effective. Until such proof is available, the next best thing is a study in which people taking the treatment are observed over time. The Nurses Health Study followed more than 4,000 nurses who had been treated for breast cancer at least 12 months earlier. The result: Nurses who took aspirin were significantly less likely to die of breast cancer and to have cancer recur at another site. After adjusting for cancer stage, menopausal status, body mass, and hormone sensitivity of the tumor, women who took aspirin seven days a week were 43% less likely to die of breast cancer. The findings may apply only to women who survive at least four years after breast cancer treatment. But since 90% of women diagnosed with breast cancer survive at least five years, “our findings have considerable clinical importance,” conclude researchers Michelle D. Holmes, MD, DrPH,
