Does adalimumab have side-effects?
In the 1380 patients receiving adalimumab in the detailed clinical trials described above common side-effects included, injection site reaction, headaches and rashes. Many of these effects were transient and only 0.2% of patients had to stop treatment because of the most common side-effect of injection site reaction. These localised skin reactions usually disappear after a few injections. Possibly the most serious side-effects to be considered with TNF-blocking treatment is that of infections. TNF plays an important helpful role in the body to fight infections. Studies of adalimumab have shown, as with other TNF-blocking drugs, a slight increase in serious infections such as pneumonia, pyelonephritis or joint infections. In particular, TNF-blocking drugs are associated with re-activation of previously undetected infections with tuberculosis (TB, previously known as consumption). Therefore, before taking adalimumab, or any TNF blocker, you will be asked about any previous infections, or
