Does abstinence from smoking or a transdermal nicotine system influence atracurium-induced neuromuscular block?
Author(s): Puura AI, Rorarius MG, Laippala P, Baer GA Affiliation(s): Department of Anaesthesia, Hatanpaa Municipal Hospital of Tampere, Finland. puura@sci.fi Publication date & source: 1998-08, Anesth Analg., 87(2):430-3. Publication type: Clinical Trial; Randomized Controlled Trial The purpose of the present study was to investigate the interaction of chronic smoking and the actions of atracurium (ATR). Twenty nonsmokers (NON-SMOK) were compared with 80 smokers, who were randomized into three groups: 30 patients received 21 mg/d transdermal nicotine system > or = 10 h before fentanyl/thiopental/N2O/O2/isoflurane anesthesia (TD-NICO), whereas the abstinent group received a placebo transdermal system (ABST, n = 30). The TD-NICO and ABST groups refrained from smoking for at least 10 h before the induction of anesthesia. A third group was allowed to smoke until 1-3 h before anesthesia (SMOK, n = 20). Neuromuscular block was monitored using a Relaxograph (Datex, Helsinki, Finland). The el
Related Questions
- How can you "diminish" the influence of Judeo-Christian religious symbols in the Golden Dawn system? Isn’t the Golden Dawn a form of esoteric Christianity?
- How can the SuperFlush System really flush the engine without running it? Won the thermostat block part of the engine?
- Can cigarette size and nicotine content influence smoking and puffing rates?
