Does a screen negative result mean the infant is not at risk for that condition?
No. Many factors can contribute to a negative result in the newborn screen. Some of theselate onset of the condition, transfusion, TPN, mislabeling of the specimencan result in a false-negative for that child. No child displaying symptoms for one of the conditions in the screening panel should be judged not-at-risk for that condition. All possibilities, including a false-negative newborn screen, should be considered when evaluating a sick infant.
