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Does a dose of zoster vaccine need to be repeated if administered by the intramuscular route instead of the subQ route?

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Does a dose of zoster vaccine need to be repeated if administered by the intramuscular route instead of the subQ route?

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No. Vaccines should always be given by the route recommended by the manufacturer because data regarding safety and efficacy of alternate routes are limited. If a dose of vaccine is inadvertently given by the wrong route, ACIP recommends that it be counted as valid. There are two exceptions to this recommendation: hepatitis B or rabies vaccine given by any route other than IM should not be counted as valid and should be repeated (http://www.cdc.gov/mmwr/PDF/rr/rr5515.pdf, pages 18-19).

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