Does a child who developes a mild rash, i.e. vesicles, following MMRV, need to be isolated?
If a child developes vesicles following MMRV, it could be a vaccine associated rash, it could be breakthrough varicella, or it could be something else entirely. You should use your clinical judgment regarding the type and number of lesions to make this diagnosis. Most vaccine-associated lesions are maculopapular. If the diagnosis is breakthrough disease, treat this like wild-type varicella. Vaccine recipients in this situation should restrict contact with immunosuppressed persons who are susceptible to varicella.
