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Do you have a recommended protocol for front-end sample processing for producing DNA fragments enriched for methylation?

April 26, 2017dna enriched fragments front-end Methylation producing Protocol recommended sample

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Do you have a recommended protocol for front-end sample processing for producing DNA fragments enriched for methylation?

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Yes, we recommend the MeDIP (methylated DNA immunoprecipitation) protocol (Nat Genet. 2005 Aug;37(8):853-62) followed by amplification if necessary. Please contact NimbleGen’s Technical Services for a detailed sample preparation protocol.