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Do you also offer ultrafiltration as a plasma protein binding method?

April 26, 2017Binding method Offer Plasma protein ultrafiltration

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Do you also offer ultrafiltration as a plasma protein binding method?

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Yes, in addition to equilibrium dialysis, we offer an ultrafiltration protocol to analyze your compound by LC-MS/MS or HPLC after it has been incubated in a plasma solution and centrifuged through filters excluding proteins of >12,000 daltons. We recommend equilibrium dialysis over ultracentrifugation because it has the ability to establish a true equilibrium and therefore provides more accurate results.