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Do trophic factor secreting neural progenitor transplants enhance phrenic motor output and prolong motor neuron survival?

April 26, 2017enhance Factor motor neural output phrenic progenitor secreting transplants trophic

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Do trophic factor secreting neural progenitor transplants enhance phrenic motor output and prolong motor neuron survival?

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In collaboration with the laboratory of C. Svendsen, we are using transplants of stem cells capable of producing and secreting relevant trophic factors (eg. BDNF, VEGF, GDNF) to protect and prolong survival of phrenic motor neurons during disease progression.