Do the gadolinium-based contrast agents cause Nephrogenic Systemic Fibrosis (NSF)?
The reports the FDA has received, the published report of gadolinium deposits in the skin of patients with NSF/NFD, and other published reports suggest that gadolinium based contrast agents play a role in the development of NSF in patients with acute or chronic severe kidney insufficiency or kidney dysfunction due to the hepato-renal syndrome or in the perioperative liver transplantation period, though there is no definitive diagnosis.
